Basic and Translational
Hu S, Du MQ, Park SM, Alcivar AA, Qu L, Gupta S, Tang J, Baens M, Ye HT, Lee TH, Marynen P, Riley JL, Yang X. cIAP2 is a ubiquitin protein ligase for Bcl10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas. J Clin Invest. 2006 Jan;116(1):174-81.
Highlighted in this issue. *Commentary by Bertoni F. and Zucca E. Delving deeper into MALT lymphoma biology. J Clin Invest. 2006 Jan;116(1):22-6.
Highlighted by MedicalNewsToday: How Chromosomal Leap Frog Causes Cancer In B Cells.
Sun H, Gong S, Carmody RJ, Hiliad A, Li L, Sun J, Kong L, Xu L, Hiliard B, Hu S, Shen H, Yang X, Chen Y. TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis. Cell. 2008 May 2;133(3):415-26. doi: 10.1016/j.cell.2008.03.026.
Highlighted in this issue. *Commentary by Freundt, EC, Bidere N, and Lenardo, MJ. A different TIPE of immune homeostasis. Cell. 2008 May 2;401-2
Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman AL, Aifantis I, Boccalatte F, Wang L, Jin M, Khoury JD, Wang W, Hu S, Yuan Y, Wang E, Yuan J, Janz S, Colgan JD, Habelhach H, Waldschmidt TJ, Muschen M, Bagg A, Darbo B, Zhao C. Coactivation of NF-kB and Notch signaling is sufficient to induce B cell transformation and enables B-myeloid conversion. Blood 2020 Jan 9;135(2):108-120. doi: 10.1182/blood.2019001438. PMID: 31697816
Yu F, He H, Nastoupil L, Xu-Monette ZY, Pham K, Liang Y, Chen G, Fowler NH, Yin CC, Tan D, Yang Y, Hu S, Young KH, Pham LV, You MJ. Targetable vulnerability of deregulated FoxM1/PLK1 signaling axis in diffuse large B-cell lymphoma. Am J Cancer Res 2022 Oct 15;12(10):4666-4679. PMID: 36381323.
Hu S, Vincenz C, Buller M, Dixit VM. A novel family of viral death effector domain- containing molecules that inhibit both CD95 and TNFR1-induced apoptosis. J Biol Chem. 1997 Apr 11;272(15):9621-4. doi: 10.1074/jbc.272.15.9621. PMID: 9092488
Hu S, Vincenz C, Ni J, Gentz R, Dixit VM. I-FLICE, a novel inhibitor of TNFR1 and CD95- induced apoptosis. J Biol Chem. 1997 Jul 11;272(28):17255-7. doi: 10.1074/jbc.272.28.17255. PMID: 9211860
Hu S, Snipas SJ, Vincenz C, Salvesen G, Dixit VM. Caspase-14 is a novel developmentally regulated protease. J Biol Chem. 1998 Nov 6;273(45):29648-53. doi: 10.1074/jbc.273.45.29648. PMID: 9792675
Hu S, Yang X. dFADD is a novel death domain-containing adaptor for the drosophila caspase DREDD. J Biol Chem. 2000 Oct 6;275(40):30761-4. doi: 10.1074/jbc.C000341200. PMID: 10934188
Hu S, Yang X. Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO. J Biol Chem. 2003 Mar 21;278(12):10055-60. doi: 10.1074/jbc.M207197200. PMID: 12525502
Mei Y, Alcivar A, Hu S, Yang X. The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2. J Biol Chem. 2011 Oct 14;286(41):35380-7. doi: 10.1074/jbc.M111.282020. PMID: 21849505
Alcivar AA, Hu S, Tang J, Yang X. DEDD and DEDD2 associate with caspase-8/10 and signal cell death. Oncogene. 2003 Jan 16;22(2):291-7. doi: 10.1038/sj.onc.1206099. PMID: 12527898
Hu S, Alcivar AA, Qu L, Tang J, Yang X. cIAP2 inhibits antigen receptor signaling by targeting Bcl10 for degradation. Cell Cycle. 2006 Jul;5(13):1438-42. doi: 10.4161/cc.5.13.2866. PMID: 16775419. PMID: 16775419
Hu S, Tamada K, Ni J, Vincenz C, Chen, L. Characterization of TNFRSF19, a novel member of tumor necrosis factor receptor superfamily. Genomics 1999 Nov 15;62(1):103-7. doi: 10.1006/geno.1999.5979. 10585776. PMID: 10585776
Guo R, Ward PA, Hu S, McDuffie JE, Huber-Lang M, Shi MM. Molecular cloning and characterization of a novel human CC chemokine, SCYA26. Genomics 1999 Jun 15;58(3):313-7. doi: 10.1006/geno.1999.5837. PMID: 10373330
Park SM, Hu S, Lee TH, Yang X. Ubiquitination mediated by inhibitor of apoptosis proteins. Methods Enzymol. 2008;446:225-35. doi: 10.1016/S0076-6879(08)01613-3. PMID: 18603125
Highlighted in this issue. *Commentary by Bertoni F. and Zucca E. Delving deeper into MALT lymphoma biology. J Clin Invest. 2006 Jan;116(1):22-6.
Highlighted by MedicalNewsToday: How Chromosomal Leap Frog Causes Cancer In B Cells.
Sun H, Gong S, Carmody RJ, Hiliad A, Li L, Sun J, Kong L, Xu L, Hiliard B, Hu S, Shen H, Yang X, Chen Y. TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis. Cell. 2008 May 2;133(3):415-26. doi: 10.1016/j.cell.2008.03.026.
Highlighted in this issue. *Commentary by Freundt, EC, Bidere N, and Lenardo, MJ. A different TIPE of immune homeostasis. Cell. 2008 May 2;401-2
Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman AL, Aifantis I, Boccalatte F, Wang L, Jin M, Khoury JD, Wang W, Hu S, Yuan Y, Wang E, Yuan J, Janz S, Colgan JD, Habelhach H, Waldschmidt TJ, Muschen M, Bagg A, Darbo B, Zhao C. Coactivation of NF-kB and Notch signaling is sufficient to induce B cell transformation and enables B-myeloid conversion. Blood 2020 Jan 9;135(2):108-120. doi: 10.1182/blood.2019001438. PMID: 31697816
Yu F, He H, Nastoupil L, Xu-Monette ZY, Pham K, Liang Y, Chen G, Fowler NH, Yin CC, Tan D, Yang Y, Hu S, Young KH, Pham LV, You MJ. Targetable vulnerability of deregulated FoxM1/PLK1 signaling axis in diffuse large B-cell lymphoma. Am J Cancer Res 2022 Oct 15;12(10):4666-4679. PMID: 36381323.
Hu S, Vincenz C, Buller M, Dixit VM. A novel family of viral death effector domain- containing molecules that inhibit both CD95 and TNFR1-induced apoptosis. J Biol Chem. 1997 Apr 11;272(15):9621-4. doi: 10.1074/jbc.272.15.9621. PMID: 9092488
Hu S, Vincenz C, Ni J, Gentz R, Dixit VM. I-FLICE, a novel inhibitor of TNFR1 and CD95- induced apoptosis. J Biol Chem. 1997 Jul 11;272(28):17255-7. doi: 10.1074/jbc.272.28.17255. PMID: 9211860
Hu S, Snipas SJ, Vincenz C, Salvesen G, Dixit VM. Caspase-14 is a novel developmentally regulated protease. J Biol Chem. 1998 Nov 6;273(45):29648-53. doi: 10.1074/jbc.273.45.29648. PMID: 9792675
Hu S, Yang X. dFADD is a novel death domain-containing adaptor for the drosophila caspase DREDD. J Biol Chem. 2000 Oct 6;275(40):30761-4. doi: 10.1074/jbc.C000341200. PMID: 10934188
Hu S, Yang X. Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO. J Biol Chem. 2003 Mar 21;278(12):10055-60. doi: 10.1074/jbc.M207197200. PMID: 12525502
Mei Y, Alcivar A, Hu S, Yang X. The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2. J Biol Chem. 2011 Oct 14;286(41):35380-7. doi: 10.1074/jbc.M111.282020. PMID: 21849505
Alcivar AA, Hu S, Tang J, Yang X. DEDD and DEDD2 associate with caspase-8/10 and signal cell death. Oncogene. 2003 Jan 16;22(2):291-7. doi: 10.1038/sj.onc.1206099. PMID: 12527898
Hu S, Alcivar AA, Qu L, Tang J, Yang X. cIAP2 inhibits antigen receptor signaling by targeting Bcl10 for degradation. Cell Cycle. 2006 Jul;5(13):1438-42. doi: 10.4161/cc.5.13.2866. PMID: 16775419. PMID: 16775419
Hu S, Tamada K, Ni J, Vincenz C, Chen, L. Characterization of TNFRSF19, a novel member of tumor necrosis factor receptor superfamily. Genomics 1999 Nov 15;62(1):103-7. doi: 10.1006/geno.1999.5979. 10585776. PMID: 10585776
Guo R, Ward PA, Hu S, McDuffie JE, Huber-Lang M, Shi MM. Molecular cloning and characterization of a novel human CC chemokine, SCYA26. Genomics 1999 Jun 15;58(3):313-7. doi: 10.1006/geno.1999.5837. PMID: 10373330
Park SM, Hu S, Lee TH, Yang X. Ubiquitination mediated by inhibitor of apoptosis proteins. Methods Enzymol. 2008;446:225-35. doi: 10.1016/S0076-6879(08)01613-3. PMID: 18603125