B-cell lymphoma/leukemia
Hu S, Du MQ, Park SM, Alcivar AA, Qu L, Gupta S, Tang J, Baens M, Ye HT, Lee TH, Marynen P, Riley JL, Yang X. cIAP2 is a ubiquitin protein ligase for Bcl10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas. J Clin Invest. 2006 Jan;116(1):174-81.
Highlighted in this issue. *Commentary by Bertoni F. and Zucca E. Delving deeper into MALT lymphoma biology. J Clin Invest. 2006 Jan;116(1):22-6.
Highlighted by MedicalNewsToday: How Chromosomal Leap Frog Causes Cancer In B Cells.
Hu S, Xu-Monette ZY, Balasubramanyam A, Manyam GC, Visco C, Tzankov A, Liu WM, Miranda RN, Zhang L, Montes-Moreno S, Dybkær K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huang Q, Huh J, Ai W, Ponzoni M, Ferreri AJ, Zhao X, Winter JN, Zhang M, Li L, Møller MB, Piris MA, Li Y, Go RS, Wu L, Medeiros LJ, Young KH. CD30-expression defines a novel subgroup of diffuse large B-cell lymphoma with favorable prognosis and distinct gene expression signature: a report from the International DLBCL Rituximab-CHOP Consortium Program study. Blood. 2013 Apr 4:121(4):2715-24. doi: 10.1182/blood-2012- 10-461848.
Highlighted in this issue. *Commentary by Chan, WC. CD30, another useful predictor of survival in DLBCL? Blood. 2013 May 121:2580-2
Hu S, Xu-Monette ZY, Tzankov A, Green T, Wu L, Balasubramanyam A, Liu WM, Visco C, Li Y, Miranda RN, Montes-Moreno S, Dybkær K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, Zhao X, van Krieken JH, Huang Q, Huh J, Ai W, Ponzoni M, Ferreri AJM, Zhou F, Slack GW, Gascoyne RD, Tu M, Variakojis D, Chen W, Go RS, Piris MA, Møller MB, Medeiros LJ, Young KH. MYC/BCL2 protein co-expression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from the International DLBCL Rituximab-CHOP Consortium Program. Blood. 2013 May 16;121(20):4021-31. Quiz 4250. doi: 10.1182/blood-2012- 10-460063.
Plenary Paper. CME article. CME Questions. Blood. 2013 May 121:4250
Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman AL, Aifantis I, Boccalatte F, Wang L, Jin M, Khoury JD, Wang W, Hu S, Yuan Y, Wang E, Yuan J, Janz S, Colgan JD, Habelhach H, Waldschmidt TJ, Muschen M, Bagg A, Darbo B, Zhao C. Coactivation of NF-kB and Notch signaling is sufficient to induce B cell transformation and enables B-myeloid conversion. Blood 2020 Jan 9;135(2):108-120. doi: 10.1182/blood.2019001438. PMID: 31697816
Chen Z, Hu S. MYC/BCL2 double-hit lymphoma mimicking acute leukemia at initial presentation. Blood. 2016 Feb 25;127(8):1072. doi: 10.1182/blood-2015-11-683730. PMID: 27351033
Zheng L, Hu S. Philadelphia chromosome-positive B-lymphoblastic lymphoma involves genitourinary system and bone at initial diagnosis and at relapse. Blood. 2017 Sep 21;130(12):1483. doi: 10.1182/blood-2017-05-785626. PMID: 28935645
Liu H, Hu S. EBV-positive ALK-positive large B-cell lymphoma. Blood. 2021 Dec 23;138(25):2741. doi: 10.1182/blood.2021013595. PMID: 34940813.
Hu Z, Medeiros LJ, Chen Z, Chen W, Li S, Konoplev SN, Lu X, Lan V Pham, Young KH, Wang W, Hu S. Mantle cell lymphoma with MYC rearrangement: A report of 17 patients. Am J Surg Pathol. 2017 Feb;41(2):216-224. doi: 10.1097/PAS.0000000000000758. PMID: 27776009
Hu Z, Pan Z, Chen W, Shi Y, Wang W, Yuan J, Wang E, Zhang S, Kurt H, Mai B, Zhang X, Liu H, Rios AA, Ma HY, Nguyen ND, Medeiros LJ, Hu S. Primary effusion lymphoma: a clinicopathological study of 70 cases. Cancers (Basel). 2021 Feb 19;13(4):878. doi: 10.3390/cancers13040878. PMID: 33669719.
Liu H, Xu-Monette Z, Tang G, Wang W, Kim Y, Yuan J, Chen W, Li Y, Li Y, Zhu F, Fang X, Luedke C, Medeiros LJ, Young KH, Hu S. EBV-positive high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements: a multi-institutional study. Histopathology. 2022 Feb;80(3):575-588. doi: 10.1111/his.14585. PMID: 34637146.
Liu H, Shen Q, Chang J, Hu S. Phenotypic switch in high-grade B-cell lymphoma with MYC and BCL6 rearrangements: a potential mechanism of therapeutic escape in lymphoma? Front Oncol. 021 Dec 23;11:795330. doi: 10.3389/fonc.2021.795330. eCollection 2021. PMID: 35004320
Liu H, Wang W, Tang G, Yin CC, Muzzafar T, Medeiros LJ, Hu S. Lymphomatous variant of hairy cell leukemia: a distinctive presentation mimicking low grade B-cell lymphoma. Histopathology. 2015 Nov;67(5):740-5. doi: 10.111/his.12694. PMID: 25809821
Liu H, Miao Y, Ferrajoli A, Tang G, McDonnell T, Medeiros LJ, Hu S. Leukemic phase of Richter transformation: a mimic of acute myeloid leukemia that responded to ibrutinib monotherapy. Am J Hematol. 2020 Oct;95(10):1221-1223. doi: 10.1002/ajh.25782. PMID: 32162729
Wang Z, Gong Q, Zhao Y, Xu H, Hu S, Zhang Z. EBV-positive T-cell lymphoproliferative disorder arising in a chronic pericardial hematoma: T-cell counterpart of fibrin-associated diffuse large B-cell lymphoma? Haematologica. 2020 Aug;105(8):e437-e439. doi: 10.3324/haematol.2020.252007. PMID: 32414846
Li Y, Hu S, Zuo Z, Hong M, Lin P, Li S, Konoplev S, Wang Z, Khoury JD, Young KH, Medeiros LJ, Yin CC. CD5-positive follicular lymphoma, clincopathologic correlations and outcome in 88 cases. Mod Pathol. 2015 Jun;28(6):787-98. doi: 10.1038/modpathol.2015.42. PMID: 25743023
Li Y, Hu S, Wang SA, Li S, Huh YO, Tang Z, Medeiros LJ, Tang G. The clinical significance of 8q245/MYC rearrangement in chronic lymphocytic leukemia. Mod Pathol. 2016 May;29(5):444-451. doi: 10.1038/modpathol.2016.35. PMID: 26916070
Li S, Weiss VL, Wang XJ, Desai PA, Hu S, Yin CC, Tang G, Reddy NM, Medeiros LJ, Lin P. High-grade B-cell lymphoma with MYC rearrangement and without BCL2 and BCL6 rearrangements is associated with high TP53 expression and a poor prognosis. Mod Pathol. 2016 Feb;40(2):253-61. doi: 10.1097/PAS.0000000000000542. PMID: 26448193
Wang W, Hu S, Lu X, Young KH, Medeiros LJ. Triple-hit B-cell lymphomas with MYC, BCL2 and BCL6 translocations/rearrangements: clinicopathologic features of 11 cases. Am J Surg Pathol. 2015 Aug;39(8):1132-9. doi: 10.1097/PAS.0000000000000434. PMID: 25828391
Pan Z, Hu S, Li M, Zhou Y, Kim YS, Reddy V, Sanmann JN, Chen M, Gao Z, Wang H, Yuan J. ALK-positive large B-cell lymphoma: a clinicopathologic study of 26 cases with review of additional 108 cases in the literature. Am J Surg Pathol. 2017 Jan;41(1):25-38. PMID: 27740969
Huang Y, Hu S, Larson DP, Shi M, He R, Dave BJ, Greiner TC, Fu K, McPhail ED, Ketterling RP, Medeiros LJ, Yuan J. Composite classic Hodgkin lymphoma and follicular lymphoma: a clinicopathologic study of 22 cases with review of 27 additional cases in the literature. Am J Surg Pathol. 2022 Jun 1;46(6):793-800. doi: 10.1097/PAS.0000000000001828. PMID: 35067515.
Wang X, Medeiros LJ, Lin P, Yin CC, Hu S, Thompson MA, Li S. MYC cytogenetic status correlates with expression and has prognostic significance in patients with MYC/BCL2 protein double-positive diffuse large B-cell lymphoma. Am J Surg Pathol. 2015 Sep;39(9):1250-8. Doi: 10.1097/PAS.0000000000000433. PMID: 25828389
Fang H, Chuang HH, Strati P, Hu S, Shuai W, Medeiros LJ, Wang W. Post chemotherapy histiocyte-rich pseudotumor mimicking residual lymphoma: a report of 11 cases correlating clinicopathologic and radiologic findings. Am J Surg Pathol. 2021 Feb 1;45(2):160-168. doi: 10.1097/PAS.0000000000001547. PMID: 32769427.
Wang W, Hu S. Cup-like blasts in B-lymphoblastic leukemia. Br J Hematol. 2015 Sep;170(5):596. doi: 10.111/bjh.13541. 26132718. PMID: 26132718
Miao Y, Hu S, Lu X, Li S, Wang W, Medeiros LJ, Lin P. Double-hit follicular lymphoma with MYC and BCL2 translocations: A study of 7 Cases with a review of Literature. Hum Pathol. 2016 Aug 17. pii: S0046-8177(16)30179-4. doi: 10.1016/j.humpath.2016.07.025. PMID: 27544800
Jain P, Hu S, Jabbour E, Takahashi K, Pemmaraju N, O’Brien S, Mulanovich VE, Estrov Z. Disseminated histoplasmosis as pseudo Richter’s transformation in a patient with chronic lymphocytic leukemia. Am J Hematol. 2015 Aug;90(8):752-3. doi: 10.1002/ajh.24029. PMID: 25850565
Liu W, Hu S, Konopleva M, Khoury JD, Kalhor N, Tang G, Bueso-Ramos CE, Jorgensen JL, Lin P, Medeiros LJ, Lu X. De novo MYC and BCL2 double-hit B-cell precursor acute lymphoblastic leukemia (BCP-ALL) in pediatric and young adult patients associated with poor prognosis. Pediatr Hematol Oncol. 2015 Nov;32(8):535-47. doi: 10.3109/08880018.2015.1087611. PMID: 26558423
Jiang C, Huang L, Zhou J, Li Z, Wang Y, Li S, Fu J, Huang Q, Yan Q, Huang Y, Zuo M, Hu S, Gale RP, Liang Y, Yun J, Huang Y. Epstein-Barr virus-based prognostic model in nodular sclerosis classic Hodgkin lymphoma. iScience. 2024 Jan 19;27(1):108630. doi: 10.1016/j.isci.2023.108630. PMID: 38188529
Geethakumari PR, Hoffmann MS, Pemmaraju N, Hu S, Jorgensen JL, O’Brien S, Daver N. Extremedullary B lymphoblastic leukemia/lymphoma (B-ALL/LBL): a diagnostic challenge. Clin Lymphoma Myeloma Leuk. 2014 Aug;14(4):e115-8. doi: 10.1016/j.clml.2014.01.004. 24589157
Wang XI, Yin CC, Qazilbash MH, Hu S, Lu G. Clinical significance of acquired cytogenetic clones in patients with treated follicular lymphoma. Clin Lymphoma Myeloma Leuk. 2015 May;15(5):262-9. doi: 10.1016/j.clml.2014.12.0004. PMID: 25573378
Loghavi S, Alayed K, Aladily TN, Zuo Z, Ng SB, Tang G, Hu S, Yin CC, Miranda RN, Medeiros LJ, Khoury JD. Stage, age and EBV status impact outcomes of plasmablastic lymphoma patients: a clinicopathologic analysis of 61 patients. J Hematol Oncol. 2015 Jun 10;8:65. doi: 10.1186/s13045-015-0163-z. PMID: 26055271
Deng L, Song Y, Young KH, Hu S, Ding N, Song W, Liu W, Li X, Shi Y, Huang H, Liu W, Zheng W, Wang X, Xie Y, Lin N, Tu M, Ping L, Ying Z, Zhang C, Sun Y, Zhu J. Hepatitis B virus-associated diffuse large B-cell lymphoma: unique clinical features, poor outcome, and hepatitis B surface antigen driven origin. Oncotarget. 2015 Sep 22;6(28):25061-75. doi: 10.18632/oncotarget.4677. PMID: 26314957
Ye Q, Xu-Monette ZY, Tzankov A, Deng L, Wang X, Manyam GC, Visco C, Montes-Moreno S, Zhang L, Dybkær K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WWL, van Krieken JH, Huh J, Ponzoni M, Ferreri AJ, Parsons BM, Møller MB, Piris MA, Winter JN, Medeiros LJ, Hu S, Young KH. Prognostic impact of concurrent MYC and BCL6 rearrangements and expression in de novo diffuse large B-cell lymphoma. Oncotarget. 2016 Jan 19;7(3):2401-16. doi: 10.18632/oncotarget.6262. PMID: 26573234
Liu W, Chen J, Tamayo AT, Ruan C, Li L, Zhou S, Shen C, Young KH, Westin J, Davis RE, Hu S, Medeiros LJ, Ford RI, Pham L. Preclinical efficacy and biological effects of the oral proteasome inhibitor ixazomib in diffuse large B-cell lymphoma. Oncotarget 2017 Aug 21;9(1):346-360. doi: 10.18632/oncotarget.20378. PMID: 29416618
Thakral B, Medeiros LJ, Desai P, Lin P, Yin CC, Tang G, Khoury JD, Hu S, Xu J, Loghavi S, Hu B, Oki Y, Li S. Prognostic impact of CD5 expression in diffuse large B-cell lymphoma in patients treated with Rituximab-EPOCH. Eur J Hematol. 2017 Apr;98(4):415-421. doi: 10.1111/ejh.12847. PMID: 28039906
Garces S, Khoury JD, Kanagal Shamanna R, Salem A, Wang SA, Ok CY, Hu S, Patel KP, Routbort MJ, Luthra R, Tang G, Schlette EJ, Bueso-Ramos CE, Medeiros LJ, Loghavi S. Chronic lymphocytic leukemia with proliferation centers in bone marrow is associated with younger age at initial presentation, complex karyotype and TP53 disruption. Hum Pathol 2018 Dec;82:215-231. doi: 10.1016/j.humpath.2018.07.030. PMID: 30086334
Sakhari A, Ok CY, Patel KP, Rashmi KS, Yin CC, Zuo Z, Hu S, Routbort MJ, Luthra R, Medeiros LJ, Khoury JD, Loghavi S. TP53 mutations are common in mantle cell lymphoma, including the indolent leukemic non-nodal variant. Ann Diagn Pathol. 2019 Aug;41:38-42. doi: 10.1016/j.anndiagpath.2019.05.004. PMID: 31132650
Chen Z, Sun Y, Xie W, Wang S, Hu S, Li S, Tang Z, Toruner G, Medeiros LJ, Tang G. Is hyperdiploidy a favorable cytogenetics in adults with B-lymphoblastic Leukemia? Cancer Med. 2019 Aug;8(9):4093-4099. doi: 10.1002/cam4.2255. PMID: 31173486
Shuai W, Lin P, Strati P, Patel KP, Routbort MJ, Hu S, Wei P, Khoury JD, You MJ, Loghavi S, Tang Z, Fang H, Thakral B, Medeiros LJ, Wang W. Clinicopathological characterization of chronic lymphocytic leukemia with MYD88 mutations: L265P and non-L265P mutations are associated with different features. Blood Cancer J. 2020 Aug 26;10(8):86. doi: 10.1038/s41408-020-00351-w. PMID: 32848129
Mai B, Wang W, Lin M, Hu S, Wang XI, Chen L, Wahed A, Nguyen A, Ma HY, Medeiros LJ, Hu Z. HIV-associated plasmablastic lymphoma in the era of highly active antiretroviral therapy: a single center experience of 21 patients. AIDS. 2020 Oct 1;34(12):1735-1743. doi: 10.1097/QAD.0000000000002590. PMID: 32889849.
Yu F, He H, Nastoupil L, Xu-Monette ZY, Pham K, Liang Y, Chen G, Fowler NH, Yin CC, Tan D, Yang Y, Hu S, Young KH, Pham LV, You MJ. Targetable vulnerability of deregulated FoxM1/PLK1 signaling axis in diffuse large B-cell lymphoma. Am J Cancer Res 2022 Oct 15;12(10):4666-4679. PMID: 36381323.
Wang WJ, Gehris BT, Mai B, Chen L, Hu S, You MJ, Hu Z. HHV8-negative effusion-based lymphoma in a patient with recurrent HCV hepatitis status post liver transplantation. Leuk Lymphoma. 2022 Dec;63(14):3480-3483. doi: 10.1080/10428194.2022.2123233. PMID: 36154351.
Dong Q, Wang Y, Xiu Y, Sakr H, Burnworth B, Xu D, O’Brien T, Burke J, Hu S, Zeng G, Zhao C. Clonally related composite chronic lymphocytic leukemia and mantle cell lymphoma. Br J Haematol 2023 Mar;200(5):660-664. doi: 10.1111/bjh.18565. PMID: 36375473.
Tang G, Li S, Toruner GA, Jain P, Tang Z, Hu S, Xu J, Cheng J, Robinson M, Vega F, Medeiros LJ. Clinical impact of 5’ MYC or 3’ MYC gain/loss detected by FISH in patients with aggressive B-cell lymphomas. Cancer Genet. 2023 Apr;272-273:1-8. doi: 10.1016/j.cancergen.2022.12.001. PMID: 36566629.
Al-Jumaili Z, Zhang YH, Wang WJ, Mai B, Wang XI, Ahmed A, Wang W, Hu S, You MJ, Hu Z. High-grade B-cell lymphoma with malignant effusions as the initial presentation. Am J Clin Pathol 2023 May 2;159(5):420-428. doi: 10.1093/ajcp/aqac182. PMID: 36879405.
Highlighted in this issue. *Commentary by Bertoni F. and Zucca E. Delving deeper into MALT lymphoma biology. J Clin Invest. 2006 Jan;116(1):22-6.
Highlighted by MedicalNewsToday: How Chromosomal Leap Frog Causes Cancer In B Cells.
Hu S, Xu-Monette ZY, Balasubramanyam A, Manyam GC, Visco C, Tzankov A, Liu WM, Miranda RN, Zhang L, Montes-Moreno S, Dybkær K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huang Q, Huh J, Ai W, Ponzoni M, Ferreri AJ, Zhao X, Winter JN, Zhang M, Li L, Møller MB, Piris MA, Li Y, Go RS, Wu L, Medeiros LJ, Young KH. CD30-expression defines a novel subgroup of diffuse large B-cell lymphoma with favorable prognosis and distinct gene expression signature: a report from the International DLBCL Rituximab-CHOP Consortium Program study. Blood. 2013 Apr 4:121(4):2715-24. doi: 10.1182/blood-2012- 10-461848.
Highlighted in this issue. *Commentary by Chan, WC. CD30, another useful predictor of survival in DLBCL? Blood. 2013 May 121:2580-2
Hu S, Xu-Monette ZY, Tzankov A, Green T, Wu L, Balasubramanyam A, Liu WM, Visco C, Li Y, Miranda RN, Montes-Moreno S, Dybkær K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, Zhao X, van Krieken JH, Huang Q, Huh J, Ai W, Ponzoni M, Ferreri AJM, Zhou F, Slack GW, Gascoyne RD, Tu M, Variakojis D, Chen W, Go RS, Piris MA, Møller MB, Medeiros LJ, Young KH. MYC/BCL2 protein co-expression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from the International DLBCL Rituximab-CHOP Consortium Program. Blood. 2013 May 16;121(20):4021-31. Quiz 4250. doi: 10.1182/blood-2012- 10-460063.
Plenary Paper. CME article. CME Questions. Blood. 2013 May 121:4250
Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman AL, Aifantis I, Boccalatte F, Wang L, Jin M, Khoury JD, Wang W, Hu S, Yuan Y, Wang E, Yuan J, Janz S, Colgan JD, Habelhach H, Waldschmidt TJ, Muschen M, Bagg A, Darbo B, Zhao C. Coactivation of NF-kB and Notch signaling is sufficient to induce B cell transformation and enables B-myeloid conversion. Blood 2020 Jan 9;135(2):108-120. doi: 10.1182/blood.2019001438. PMID: 31697816
Chen Z, Hu S. MYC/BCL2 double-hit lymphoma mimicking acute leukemia at initial presentation. Blood. 2016 Feb 25;127(8):1072. doi: 10.1182/blood-2015-11-683730. PMID: 27351033
Zheng L, Hu S. Philadelphia chromosome-positive B-lymphoblastic lymphoma involves genitourinary system and bone at initial diagnosis and at relapse. Blood. 2017 Sep 21;130(12):1483. doi: 10.1182/blood-2017-05-785626. PMID: 28935645
Liu H, Hu S. EBV-positive ALK-positive large B-cell lymphoma. Blood. 2021 Dec 23;138(25):2741. doi: 10.1182/blood.2021013595. PMID: 34940813.
Hu Z, Medeiros LJ, Chen Z, Chen W, Li S, Konoplev SN, Lu X, Lan V Pham, Young KH, Wang W, Hu S. Mantle cell lymphoma with MYC rearrangement: A report of 17 patients. Am J Surg Pathol. 2017 Feb;41(2):216-224. doi: 10.1097/PAS.0000000000000758. PMID: 27776009
Hu Z, Pan Z, Chen W, Shi Y, Wang W, Yuan J, Wang E, Zhang S, Kurt H, Mai B, Zhang X, Liu H, Rios AA, Ma HY, Nguyen ND, Medeiros LJ, Hu S. Primary effusion lymphoma: a clinicopathological study of 70 cases. Cancers (Basel). 2021 Feb 19;13(4):878. doi: 10.3390/cancers13040878. PMID: 33669719.
Liu H, Xu-Monette Z, Tang G, Wang W, Kim Y, Yuan J, Chen W, Li Y, Li Y, Zhu F, Fang X, Luedke C, Medeiros LJ, Young KH, Hu S. EBV-positive high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements: a multi-institutional study. Histopathology. 2022 Feb;80(3):575-588. doi: 10.1111/his.14585. PMID: 34637146.
Liu H, Shen Q, Chang J, Hu S. Phenotypic switch in high-grade B-cell lymphoma with MYC and BCL6 rearrangements: a potential mechanism of therapeutic escape in lymphoma? Front Oncol. 021 Dec 23;11:795330. doi: 10.3389/fonc.2021.795330. eCollection 2021. PMID: 35004320
Liu H, Wang W, Tang G, Yin CC, Muzzafar T, Medeiros LJ, Hu S. Lymphomatous variant of hairy cell leukemia: a distinctive presentation mimicking low grade B-cell lymphoma. Histopathology. 2015 Nov;67(5):740-5. doi: 10.111/his.12694. PMID: 25809821
Liu H, Miao Y, Ferrajoli A, Tang G, McDonnell T, Medeiros LJ, Hu S. Leukemic phase of Richter transformation: a mimic of acute myeloid leukemia that responded to ibrutinib monotherapy. Am J Hematol. 2020 Oct;95(10):1221-1223. doi: 10.1002/ajh.25782. PMID: 32162729
Wang Z, Gong Q, Zhao Y, Xu H, Hu S, Zhang Z. EBV-positive T-cell lymphoproliferative disorder arising in a chronic pericardial hematoma: T-cell counterpart of fibrin-associated diffuse large B-cell lymphoma? Haematologica. 2020 Aug;105(8):e437-e439. doi: 10.3324/haematol.2020.252007. PMID: 32414846
Li Y, Hu S, Zuo Z, Hong M, Lin P, Li S, Konoplev S, Wang Z, Khoury JD, Young KH, Medeiros LJ, Yin CC. CD5-positive follicular lymphoma, clincopathologic correlations and outcome in 88 cases. Mod Pathol. 2015 Jun;28(6):787-98. doi: 10.1038/modpathol.2015.42. PMID: 25743023
Li Y, Hu S, Wang SA, Li S, Huh YO, Tang Z, Medeiros LJ, Tang G. The clinical significance of 8q245/MYC rearrangement in chronic lymphocytic leukemia. Mod Pathol. 2016 May;29(5):444-451. doi: 10.1038/modpathol.2016.35. PMID: 26916070
Li S, Weiss VL, Wang XJ, Desai PA, Hu S, Yin CC, Tang G, Reddy NM, Medeiros LJ, Lin P. High-grade B-cell lymphoma with MYC rearrangement and without BCL2 and BCL6 rearrangements is associated with high TP53 expression and a poor prognosis. Mod Pathol. 2016 Feb;40(2):253-61. doi: 10.1097/PAS.0000000000000542. PMID: 26448193
Wang W, Hu S, Lu X, Young KH, Medeiros LJ. Triple-hit B-cell lymphomas with MYC, BCL2 and BCL6 translocations/rearrangements: clinicopathologic features of 11 cases. Am J Surg Pathol. 2015 Aug;39(8):1132-9. doi: 10.1097/PAS.0000000000000434. PMID: 25828391
Pan Z, Hu S, Li M, Zhou Y, Kim YS, Reddy V, Sanmann JN, Chen M, Gao Z, Wang H, Yuan J. ALK-positive large B-cell lymphoma: a clinicopathologic study of 26 cases with review of additional 108 cases in the literature. Am J Surg Pathol. 2017 Jan;41(1):25-38. PMID: 27740969
Huang Y, Hu S, Larson DP, Shi M, He R, Dave BJ, Greiner TC, Fu K, McPhail ED, Ketterling RP, Medeiros LJ, Yuan J. Composite classic Hodgkin lymphoma and follicular lymphoma: a clinicopathologic study of 22 cases with review of 27 additional cases in the literature. Am J Surg Pathol. 2022 Jun 1;46(6):793-800. doi: 10.1097/PAS.0000000000001828. PMID: 35067515.
Wang X, Medeiros LJ, Lin P, Yin CC, Hu S, Thompson MA, Li S. MYC cytogenetic status correlates with expression and has prognostic significance in patients with MYC/BCL2 protein double-positive diffuse large B-cell lymphoma. Am J Surg Pathol. 2015 Sep;39(9):1250-8. Doi: 10.1097/PAS.0000000000000433. PMID: 25828389
Fang H, Chuang HH, Strati P, Hu S, Shuai W, Medeiros LJ, Wang W. Post chemotherapy histiocyte-rich pseudotumor mimicking residual lymphoma: a report of 11 cases correlating clinicopathologic and radiologic findings. Am J Surg Pathol. 2021 Feb 1;45(2):160-168. doi: 10.1097/PAS.0000000000001547. PMID: 32769427.
Wang W, Hu S. Cup-like blasts in B-lymphoblastic leukemia. Br J Hematol. 2015 Sep;170(5):596. doi: 10.111/bjh.13541. 26132718. PMID: 26132718
Miao Y, Hu S, Lu X, Li S, Wang W, Medeiros LJ, Lin P. Double-hit follicular lymphoma with MYC and BCL2 translocations: A study of 7 Cases with a review of Literature. Hum Pathol. 2016 Aug 17. pii: S0046-8177(16)30179-4. doi: 10.1016/j.humpath.2016.07.025. PMID: 27544800
Jain P, Hu S, Jabbour E, Takahashi K, Pemmaraju N, O’Brien S, Mulanovich VE, Estrov Z. Disseminated histoplasmosis as pseudo Richter’s transformation in a patient with chronic lymphocytic leukemia. Am J Hematol. 2015 Aug;90(8):752-3. doi: 10.1002/ajh.24029. PMID: 25850565
Liu W, Hu S, Konopleva M, Khoury JD, Kalhor N, Tang G, Bueso-Ramos CE, Jorgensen JL, Lin P, Medeiros LJ, Lu X. De novo MYC and BCL2 double-hit B-cell precursor acute lymphoblastic leukemia (BCP-ALL) in pediatric and young adult patients associated with poor prognosis. Pediatr Hematol Oncol. 2015 Nov;32(8):535-47. doi: 10.3109/08880018.2015.1087611. PMID: 26558423
Jiang C, Huang L, Zhou J, Li Z, Wang Y, Li S, Fu J, Huang Q, Yan Q, Huang Y, Zuo M, Hu S, Gale RP, Liang Y, Yun J, Huang Y. Epstein-Barr virus-based prognostic model in nodular sclerosis classic Hodgkin lymphoma. iScience. 2024 Jan 19;27(1):108630. doi: 10.1016/j.isci.2023.108630. PMID: 38188529
Geethakumari PR, Hoffmann MS, Pemmaraju N, Hu S, Jorgensen JL, O’Brien S, Daver N. Extremedullary B lymphoblastic leukemia/lymphoma (B-ALL/LBL): a diagnostic challenge. Clin Lymphoma Myeloma Leuk. 2014 Aug;14(4):e115-8. doi: 10.1016/j.clml.2014.01.004. 24589157
Wang XI, Yin CC, Qazilbash MH, Hu S, Lu G. Clinical significance of acquired cytogenetic clones in patients with treated follicular lymphoma. Clin Lymphoma Myeloma Leuk. 2015 May;15(5):262-9. doi: 10.1016/j.clml.2014.12.0004. PMID: 25573378
Loghavi S, Alayed K, Aladily TN, Zuo Z, Ng SB, Tang G, Hu S, Yin CC, Miranda RN, Medeiros LJ, Khoury JD. Stage, age and EBV status impact outcomes of plasmablastic lymphoma patients: a clinicopathologic analysis of 61 patients. J Hematol Oncol. 2015 Jun 10;8:65. doi: 10.1186/s13045-015-0163-z. PMID: 26055271
Deng L, Song Y, Young KH, Hu S, Ding N, Song W, Liu W, Li X, Shi Y, Huang H, Liu W, Zheng W, Wang X, Xie Y, Lin N, Tu M, Ping L, Ying Z, Zhang C, Sun Y, Zhu J. Hepatitis B virus-associated diffuse large B-cell lymphoma: unique clinical features, poor outcome, and hepatitis B surface antigen driven origin. Oncotarget. 2015 Sep 22;6(28):25061-75. doi: 10.18632/oncotarget.4677. PMID: 26314957
Ye Q, Xu-Monette ZY, Tzankov A, Deng L, Wang X, Manyam GC, Visco C, Montes-Moreno S, Zhang L, Dybkær K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WWL, van Krieken JH, Huh J, Ponzoni M, Ferreri AJ, Parsons BM, Møller MB, Piris MA, Winter JN, Medeiros LJ, Hu S, Young KH. Prognostic impact of concurrent MYC and BCL6 rearrangements and expression in de novo diffuse large B-cell lymphoma. Oncotarget. 2016 Jan 19;7(3):2401-16. doi: 10.18632/oncotarget.6262. PMID: 26573234
Liu W, Chen J, Tamayo AT, Ruan C, Li L, Zhou S, Shen C, Young KH, Westin J, Davis RE, Hu S, Medeiros LJ, Ford RI, Pham L. Preclinical efficacy and biological effects of the oral proteasome inhibitor ixazomib in diffuse large B-cell lymphoma. Oncotarget 2017 Aug 21;9(1):346-360. doi: 10.18632/oncotarget.20378. PMID: 29416618
Thakral B, Medeiros LJ, Desai P, Lin P, Yin CC, Tang G, Khoury JD, Hu S, Xu J, Loghavi S, Hu B, Oki Y, Li S. Prognostic impact of CD5 expression in diffuse large B-cell lymphoma in patients treated with Rituximab-EPOCH. Eur J Hematol. 2017 Apr;98(4):415-421. doi: 10.1111/ejh.12847. PMID: 28039906
Garces S, Khoury JD, Kanagal Shamanna R, Salem A, Wang SA, Ok CY, Hu S, Patel KP, Routbort MJ, Luthra R, Tang G, Schlette EJ, Bueso-Ramos CE, Medeiros LJ, Loghavi S. Chronic lymphocytic leukemia with proliferation centers in bone marrow is associated with younger age at initial presentation, complex karyotype and TP53 disruption. Hum Pathol 2018 Dec;82:215-231. doi: 10.1016/j.humpath.2018.07.030. PMID: 30086334
Sakhari A, Ok CY, Patel KP, Rashmi KS, Yin CC, Zuo Z, Hu S, Routbort MJ, Luthra R, Medeiros LJ, Khoury JD, Loghavi S. TP53 mutations are common in mantle cell lymphoma, including the indolent leukemic non-nodal variant. Ann Diagn Pathol. 2019 Aug;41:38-42. doi: 10.1016/j.anndiagpath.2019.05.004. PMID: 31132650
Chen Z, Sun Y, Xie W, Wang S, Hu S, Li S, Tang Z, Toruner G, Medeiros LJ, Tang G. Is hyperdiploidy a favorable cytogenetics in adults with B-lymphoblastic Leukemia? Cancer Med. 2019 Aug;8(9):4093-4099. doi: 10.1002/cam4.2255. PMID: 31173486
Shuai W, Lin P, Strati P, Patel KP, Routbort MJ, Hu S, Wei P, Khoury JD, You MJ, Loghavi S, Tang Z, Fang H, Thakral B, Medeiros LJ, Wang W. Clinicopathological characterization of chronic lymphocytic leukemia with MYD88 mutations: L265P and non-L265P mutations are associated with different features. Blood Cancer J. 2020 Aug 26;10(8):86. doi: 10.1038/s41408-020-00351-w. PMID: 32848129
Mai B, Wang W, Lin M, Hu S, Wang XI, Chen L, Wahed A, Nguyen A, Ma HY, Medeiros LJ, Hu Z. HIV-associated plasmablastic lymphoma in the era of highly active antiretroviral therapy: a single center experience of 21 patients. AIDS. 2020 Oct 1;34(12):1735-1743. doi: 10.1097/QAD.0000000000002590. PMID: 32889849.
Yu F, He H, Nastoupil L, Xu-Monette ZY, Pham K, Liang Y, Chen G, Fowler NH, Yin CC, Tan D, Yang Y, Hu S, Young KH, Pham LV, You MJ. Targetable vulnerability of deregulated FoxM1/PLK1 signaling axis in diffuse large B-cell lymphoma. Am J Cancer Res 2022 Oct 15;12(10):4666-4679. PMID: 36381323.
Wang WJ, Gehris BT, Mai B, Chen L, Hu S, You MJ, Hu Z. HHV8-negative effusion-based lymphoma in a patient with recurrent HCV hepatitis status post liver transplantation. Leuk Lymphoma. 2022 Dec;63(14):3480-3483. doi: 10.1080/10428194.2022.2123233. PMID: 36154351.
Dong Q, Wang Y, Xiu Y, Sakr H, Burnworth B, Xu D, O’Brien T, Burke J, Hu S, Zeng G, Zhao C. Clonally related composite chronic lymphocytic leukemia and mantle cell lymphoma. Br J Haematol 2023 Mar;200(5):660-664. doi: 10.1111/bjh.18565. PMID: 36375473.
Tang G, Li S, Toruner GA, Jain P, Tang Z, Hu S, Xu J, Cheng J, Robinson M, Vega F, Medeiros LJ. Clinical impact of 5’ MYC or 3’ MYC gain/loss detected by FISH in patients with aggressive B-cell lymphomas. Cancer Genet. 2023 Apr;272-273:1-8. doi: 10.1016/j.cancergen.2022.12.001. PMID: 36566629.
Al-Jumaili Z, Zhang YH, Wang WJ, Mai B, Wang XI, Ahmed A, Wang W, Hu S, You MJ, Hu Z. High-grade B-cell lymphoma with malignant effusions as the initial presentation. Am J Clin Pathol 2023 May 2;159(5):420-428. doi: 10.1093/ajcp/aqac182. PMID: 36879405.